­RISHI  ­BIOTECH 

Bioinformatics [022-40120576,info@rishibiotech.com] :

• Biological sequence assembly and manipulation
• Genome annotation and analysis
• Biological sequence identification
• Gene finding and characterisation
• Comparative genomics: e.g. finding drug targets by comparing pathways from human and pathogen.
• Biological systems analysis
• Phylogenetic analysis (evolution of genes or proteins)
• Characterisation of gene regulatory elements
• Protein sequence annotation and characterization
• Microarray data analysis
• Drug Designing
• Rational Drug Design

We provide custom analysis to suit your requirement and services in a number of areas including:

• Automated Catalyst database updating standard
• Datasheet Catalyst massively parallel database building and searching
• Datasheet complete chemistry console
• Ensemble docking and scoring
• Grid integration for docking, scoring, and conformer generation
  

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• ·Bisulfite Sequencing Service (Methyl-Seq)
• ·Bisulfite-based DNA methylation sequencing
• ·MeDIP Sequencing Service (MeDIP-Seq)
• ·MeDIP-based DNA methylation sequencing
• ·Methylation-Specific PCR
• ·Robust PCR for smaller scale DNA methylation analysis
• ·Global 5-mC Quantification
• ·ELISA-based assay for quantitation of total methylated cytosine levels in DNA
• ·hMeDIP Sequencing Service (hMeDIP-Seq)
• ·Multi-base resolution 5-hmC sequencing
• ·True 5-hmC Sequencing Service (Hydroxymethyl-Seq)
• ·Single base resolution 5-hmC sequencing
• ·Global 5-hmC Quantification
• ·ELISA-based assay for quantitation of total hydroxymethylated cytosine levels in DNA
• ·ChIP Sequencing Service (ChIP-Seq)
• ·Genome-wide chromatin immunoprecipitation sequencing
• ·ChIP Quantitative PCR Service (ChIP-qPCR)
• ·Robust quantitative PCR for smaller scale and affordable chromatin immunoprecipitation analysis
• ·ChIP Antibody Validation Service
• ·Validation of antibodies for successful use in ChIP-PCR, ChIP-on-chip, or ChIP-seq
• ·Epigenetic Analysis
• ·Sequencing & Expression Analysis
• ·De Novo Sequencing, Re-sequencing and Targeted Sequencing
• ·Genome Resequencing Data Analysis
• ·Identification of small structural variations (SVs) such as SNPs and DIPs;
• Identification of large SVs like deletions, insertions, duplications, inversions, genomic rearrangements, Copy Number Variations (CNV) and Presence Absence Variations (PAV);
• ·Genome consensus reconstruction;
• ·Genome Wide Association Studies (GWAS);
• ·High-throughput genotyping;
• ·Molecular evolution studies.
• ·Targeted & Exome Sequencing Data Analysis
• ·Identification of small structural variations (SVs) such as SNPs and DIPs;
• Identification of large SVs like deletions, insertions, duplications, inversions, genomic rearrangements, Copy Number Variations (CNV) and Presence Absence Variations (PAV);
• Genome Wide Association Studies (GWAS);
• High-throughput genotyping;
• High-throughput development of molecular markers;
• Molecular evolution studies
• Metagenomic Sequencing Data Analysis
• ·Analysis of species composition and abundance
• ·Genome components analysis
• ·Generate non-redundant gene catalog
• ·Gene functional annotations
• ·Comparative analysis among samples
• ·Transcriptomic Data Analysis
• ·Analysis Cases:
• ·Total RNA-Seq (Whole Transcriptome) Sequencing Data Analysis
• ·RNA-Seq (mRNA) Data Analysis
• ·Small RNA Resequencing Data Analysis
• ·With our de novo Sequencing Data Analysis service, we are able to provide:
• ·Identification of the expressed genes
• ·Identification of splicing variants
• ·Determination of the gene structures
• ·Quantification of absolute and relative gene expression levels
• ·Relative expression of different alleles
• ·SNP discovery and characterization
• ·Differential expression analysis
• ·Detection of post-transcriptional edits
• ·De novo RNA sequencing
• ·Identification of microRNAs including novel microRNAs
• ·Gene Ontology (GO) enrichment analysis
• ·Novel microRNA prediction
• ·Expression quantitation of known and novel microRNA
• ·Differential expression analysis of known and novel microRNA
• ·Target gene prediction and network/pathway analysis